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Empfehlung1

Urethral reconstruction with cells of the oral mucosa

Advantages: (+):

- very good healing chances
- gentle and state-of-the-art treatment procedure
- no extraction of mucoperiosteal flap
- officially approved pharmaceutical product for innovative therapies

Disadvantages (-):

- available in a limited number of hospitals to date

Urethral reconstruction using oral mucosa

Advantages (+):

- very good healing chances

Disadvantages (-):

- large scale extraction of oral mucosa
- often scar tissue in the mouth
- can limit the flexibility of the lower lip,
- can lead to numbness in the oral, cheek and lip region,
- can lead to changes in facial expression or problems with speaking and drinking,
- can lead to increased salivation
- prolonged time of surgery due to two surgical procedures on the urethra and the mouth,
- risk of damage to the front of the salivary glands
- in case of relapse there is not enough oral mucosa tissue left, or oral mucosa needs to be extracted from the already scared / injured oral cavity
- the procedure has not been tested with independent, prospective studies
- many doctors lack the skills for oral surgery, urologists usually do not receive training for surgeries in the oral area.

methode3

Urethral dilation
Urethral sounding

Advantages (+):

- possibility for outpatient treatment without anesthesia

Disadvantages (-):

- very high probability for relapse and complications
- the procedure requires regular repetitions
- repeat procedures worsen the clinical picture and lead to long stretches of strictures
- long-term healing chances get worse with every procedure

Methode4

Incision of the urethra (urethrotomy)

Advantages (+):

- simple procedure
- ater first-time appearance of the disease this procedure is indicated

Disadvantages (-):

- probability for relapse lies with 70 % - 100 %,
- every incision in the scarred urethra will lead to a new scar with another stricture which in turn leads to even longer and bigger scarring,
- it will be more and more difficult to create a tube / an opening for the urine flow with scarred tissue,
- the clinical picture gets worse with every procedure
- repeat incisions can lead to irreversible damage of the urethra.